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Scientific Programmes
Bipolar Disorder
COORDINATOR: DR. EDUARD VIETA (G25 – Hospital Clínic de Barcelona)
As part of the most relevant results of the groups forming the programme, we should stress the 32 ar- ticles in the first decile. The findings of these studies have been published in journals of the highest pres- tige such as The Lancet, the American Journal of Psychiatry, British Journal of Psychiatry, European Neuropsychopharmacology, International Journal
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sode improve clinical/functional outcomes? Acta Psychiatr Scand. 2015 Feb;131(2):100-10.
Eduard Vieta appears in the list of biomedical field researchers most widely cited in scientific publi- cations (Highly Cited Researchers 2015), drawn up by the international agency Thomson Reuters, 2015.
of Neuropsychopharmacology, Psychological Med- icine, Schizophrenia Bulletin and Acta Psychiatrica Scandinavica, amongst others.
The bipolar disorder programme has a high degree of internationalisation and scientific productivity. In 2015 we should stress the epidemiological coop- erative work done between CIBERSAM groups and other CIBERs, as well as national and international collaboration.
Apart from this, the groups in the bipolar programme have been particularly active in getting new projects under way, as well as finding new funding. In 2015 competitive financing was obtained for 26 projects, both from public bodies (MINECO- Instituto de Salud Carlos III, Unión Europea, Comunidad de Madrid, Generalitat de Cataluña, Generalitat Valenciana, Gobierno Vasco) and from other national institutions (UAM-Banco Santander with the United States) and international bodies (NARSAD, The Stanley Medical Research Institute).
Some of the awards and honours received by mem- bers of the programme are:
• Appointment as “Honoris Causa” Doctor by the Universitat de València (UV), Dr. Eduard Vieta.
• Reference Researcher Award, Sociedad Española de Psiquiatría Biológica (SEPB), Dr. Antoni Bena- barre.
• Emerging Researcher Award, Sociedad Española de Psiquiatría Biológica (SEPB), Dr. Íria Grande.
• Extraordinary award for doctoral thesis 2015, Dr. Iria Grande.
• 1st Award for best international article Jornadas de investigación 2015 HOSPITAL UNIVERSITARIO ARABA: Zorrilla I., Aguado J., Haro J.M., Barbeito S., López Zurbano S., Ortiz A., López P., Gonzá- lez-Pinto A. Cannabis and bipolar disorder: Does quitting cannabis use during manic/mixed epi-
Some of the scientific achievements obtained by the different groups in the programme are:
• Characterisation of the functional brain changes in the different phases of bipolar disorder.
• As members of the Global Burden of Disease network we have taken part in the publication of the Global Burden of Disease study 2013, in The Lancet.
• Proving the predictive value of the cognitive re- serve in bipolar disorder.
• Preparation of clinical recommendations for work with relatives of patients with bipolar disorder.
• Preparation of a document on bipolar disorder which stresses the importance of tackling the dis- eases translationally.
• A collaborative study with the NASA which has enabled making progress in knowledge of the mechanisms involved in the age of starting with bipolar disorder.
• Functional rehabilitation improves the autonomy and general function of patients with bipolar dis- order.
• Identification of risk/protection factors involved in first psychotic episodes, related with BDNF and TrkB receptors.
• Identification of new biomarkers, therapeutic tar- gets and innovative action mechanisms for treat- ing bipolar disorder.
• Finally, as members of the Cognitive Decline Group of the European Innovation Partnership for Active and Healthy Ageing (EIPAHA) we take an active part in defining a clinically useful position on Mild Cognitive Decline.
20 I Annual report 2015 I CIBERSAM