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Most relevant • GRIFFeth Rj, CaRReteRo j, buRks dj.. Insulin receptor substrate 2 is required for testi- 
cular development.PLoS One. 2013;May 31(8(5)):e62103.
scientific 
• González-naVaRRo h, VInué á, sanz Mj, delGado M, Pozo Ma, seRRano M, buRks dj, andRés 
articles
V.. Increased dosage of Ink4/Arf protects against glucose intolerance and insulin 
resistance associated with aging.Aging Cell. 2013 ;Feb(12(1)):102-11.

• I R, e á, C a, C s, P b, V h- 
sabelonCeRolVIRalVaRezaRlosCostaaRMenanzedRoaRRIoeRónICauR
tado, deboRah buRks, enRIque blázquez. Insulin-receptor substrate-2 (IRS-2) required 
for mantaining glucokinase and glucokinase regulatory protein expresion in mouse 

liverPloS one. 2013;8.

• heRnández C, sIMó R, European Consortium for the Early Treatment of Diabetic Re- 

tinopathy (EUROCONDOR). Somatostatin replacement: a new strategy for treating 
diabetic retinopathy.Curr Med Chem. 2013;20(26):3251-7.

• aRRoba aI, ReVuelta-CeRVantes j, Menes l, González-RodRíGuez á, PaRdo V, de la VIlla P 

et al.. Loss of protein tyrosine phosphatase 1B increases IGF-I receptor tyrosine 
phosphorylation but does not rescue retinal defects in IRS2-deficient mice.Invest 

Ophthalmol Vis Sci. 2013 Jun 19;54(6):4215-25.




In addition to the work published by our group in 2013 we have continued to work 
Highlights
as active members of the European Consortium for the Early Treatment of Diabetic 

Retinopathy (EUROCONDOR, FP7-278040-2. FP7-HEALTH-2011: 2012-2015 Pro- 

gramme 3) and the “Innovative strategies to generate human hepatocytes” “In- 
novaLIV” consortium (FP7: 2011-2014, Programme 3). Veronica Moreno Viedma 

successfully defended her PhD thesis entitled “Role of IRS2 in Obesity and Adipo- 
genesis” (May, 2013) and Dr Luke Noon performed a successful 1 year DIAbetes 

Transnational Research Advancement for INvestigators (DIATRAIN) Fellowship in 

the laboratory of Professor Scott Friedman at The Icahn School of Medicine at 
Mount Sinai (New York, USA).




















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