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of neuropsychological / psychopathology alterations and cognitive assessment • Integrity of the auto- nomic nervous system during VM collaboration with CIBER-BBN-SEPAR. • Feasibility, safety and efficacy of neurocognitive rehabilitation in patients with VM.
5. Study of the patient-ventilator interaction during VM: Impact of asynchronies • Characterization of asyn- chronies • Parameters involved • Consequences of poor patient interaction / ventilator
Most relevant scientific articles
Research Groups
garCía-Prieto e., LóPez-aguiLar J., Parra-ruiz D., aMa- Do-roDríguez L., LóPez-aLonso i., BLazquez-Prieto J. et aL. Impact of Recruitment on Static and Dynamic Lung Strain in Acute Respiratory Distress Syndrome. Anesthesiology. 2015
quiLez M.e., roDríguez-gonzáLez r., turon M., Fernán- Dez-gonzaLo s., viLLar J., KaCMareK r.M. et aL. Moderate peep after tracheal lipopolysaccharide instillation prevents inflammation and modifies the pattern of brain neuronal ac- tivation. Shock. 2015;44(6):601-608.
Murias g., De haro C., BLanCh L.. Does this ventilated pa- tient have asynchronies? Recognizing reverse triggering
Highlights
Our goal is to raise awareness of respiratory diseas- es in critically ill patients using a multidisciplinary and translational approach. Our projects are aimed at transferring to society and market developments that help to improve health and generate wealth. We have patents and a spin-off. We cooperate with na- tional / international networks and innovation in clin- ical studies.
NOTABLE RESULTS Development of translational projects funded under AES Program: PI15 / 02204. Immunomodulatory cell therapy in sepsis. ISCIII (2016-2018) • PI13 / 02204: Influence of persistent decoupling patient/ventilator in cognitive and psy- chopathological alterations in critically ill patients: multicenter clinical and mechanistic study. (CIBERES Groups 29-33) • PI13 / 02189. Translational research in the fragile patient undergoing MV: In experimen- tal models therapeutic opportunities. • PI12 / 02548 transplantation of alveolar type II cells in experimen- tal models of ALI (CIBERES Groups 23-33).
International projects funded in context of moni- toring of critically ill patients: EU THALEA I and II “Telemonitoring and Telemedicine for Hospitals As-
and entrainment at the bedside. Intensive Care Medicine. 2015;:1-4.
Martín-LoeChes i., Povoa P., roDríguez a., CurCio D., su- arez D., Mira J.-P. et aL. Incidence and prognosis of venti- lator-associated tracheobronchitis (TAVeM): A multicentre, prospective, observational study. The Lancet Respiratory Medicine. 2015
BLanCh L, viLLagra a, saLes B, Montanya J, LuCangeLo u, LuJán M et aL. Asynchronies during mechanical ventilation are associated with mortality.Intensive care medicine. 2015
sisted by ICT for Life saving co-morbid Patients in Europe As part of a Personalised Patient Care Pro- gram of the EU” • EU-Egypt partnership for improved monitoring of critically ill patients. • Collaborative CIBERES-SEPAR-CIBERBBN: Effects of an early neurocognitive intervention on patient-ventilator in- teraction and stress in critically ill Patients receiving MV.
OTHER ACHIEVEMENTS: Global Sepsis Award in the category for non-governmental Organizations, health care provider groups and patient advocacy groups (A Artigas) • ESICM established investigator award Cell therapies for the treatment of ALI in an experimental model (A Artigas) • Grant Taulí Excel- lence: Development of an experimental model of controlled asynchronies to analyse the mechanisms involved in the cognitive or psychopathology in pa- tients ventilated. (2015-2016) IP: J Lopez-Aguilar • Agreement with Grífols. Effect of Antithrombin in an in vitro model of ALI • Grant for research initiation CIBERES 2015 • Development of multi-center clinical trials in the field of pneumonia associated with MV.
Institution: Corporación Sanitaria Parc Taulí · Contact: Parc Taulí, S/N. 08208 Sabadell Tel.: 93 723 10 10 ext. 22229 · E.mail: [email protected]
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