Page 42 - CIBERES-2015-eng

Research Groups
Group 4
Programme: Sleep Apnoeas Syndrome / Lung Cancer / COPD Lead Researcher: González Mangado, Nicolás
Group members
STAFF MEMBERS: Fernández Arias, José | Pérez Rial, Sandra.
ASSOCIATED MEMBERS: Fernández Ormaechea, Itziar | Peces Barba Romero, Germán | Rodríguez Nieto,
María Jesús | Seijo Maceiras, Luis Miguel | Suárez Sipmann, Fernando | Villar Álvarez, Felipe.
Main lines of research
• CRP OF SLEEP APNEA: OSA as a risk factor for cardiovascular morbidity and mortality, OSA as a risk factor for cancer and SAHS in women.
• CRP OF CANCER: Early detection program in sub- jects at high risk for emphysema or lung function impairment. Risk of each individual as his smok- ing habit and personal and family history. Influ- ence of associated diseases, especially chronic obstructive pulmonary disease (COPD) and em- physema over the risk of developing lung cancer and its prognosis. Genetic and molecular factors that determine the risk profile of each individual.
• CRP OF COPD: Susceptibility to the development of lung injury and its evolution up to present the well established disease in animal models. Identi- fication of the key biomarkers in the development and progression of the disease and its translation to the clinic. Cohorts of COPD patients with early onset and with late-stage severe COPD. New ther- apeutic targets based on the utilization of growth factors in experimental models of disease and in endoscopic implantation in patients of spirals and valves for the treatment of emphysema .
42 I Annual report 2015 I CIBERES