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Most relevant scientific articles
Research Groups
DoMeneCh M., ruiz s., MosCoso M., garCía e.. In vitro biofilm development of Streptococcus pneumoniae and formation of choline-binding protein-DNA complexes. En- vironmental Microbiology Reports. 2015;7(5):715-727.
De graCia retaMosa M., Diez-Martínez r., Maestro B., garCía-FernánDez e., De WaaL B., MeiJer e.W. et aL. Aro- matic Esters of Bicyclic Amines as Antimicrobials against Streptococcus pneumoniae. Angewandte Chemie - Inter- national Edition. 2015;54(46):13673-13677.
riCo-Lastres P., Diez-Martínez r., igLesias-Bexiga M., BustaMante n., aLDriDge C., heseK D. et aL. Substrate recognition and catalysis by LytB, a pneumococcal pep-
Highlights
1) In late 2015, the patent Application No. 13/516,617 and entitled “DETECTION OF STREPTOCOCCUS PNEUMONIAE THROUGH MAGNETO-AMPEROMET- RIC GENOSENSORS EMPLOYING SPECIFIC PRIM- ERS ANO PROBES FOR THE LYTA GENE” has been approved by the United States Patent and Trade- mark Office.
2) Streptococcus pneumoniae are usually found as asymptomatic colonizers of the upper respira- toru tract in humans. In addition, this bacterium is
tidoglycan hydrolase involved in virulence. Scientific Re- ports. 2015;5:-.
raMos-seviLLano e., urzainqui a., CaMPuzano s., Mos- Coso M., gonzáLez-CaMaCho F., DoMeneCh M. et aL. Plei- otropic effects of cell wall amidase LytA on Streptococcus pneumoniae sensitivity to the host immune response. In- fection and Immunity. 2015;83(2):591-603.
aguinagaLDe L, Díez-Martínez r, yuste J, royo i, giL C, Lasa í et aL. Auranofin efficacy against MDR Strep- tococcus pneumoniae and Staphylococcus aureus in- fections.The Journal of antimicrobial chemotherapy. 2015;70(9):2608-17.
endowed with a high virulnce potential and is one of the most common etiological agents of respira- tory and life-threatening infections. Dr. Pedro García from our group is one of the invited contributors to the book “Streptococcus pneumoniae: Molecular mechanisms of host-pathogen interactions” (2015; Academic Press; ISBN: 978-0-12-410530-0) that provides a comprehensive overview of our existing knowledge on S. pneumoniae disease pathogenesis.
Institution: Agencia Estatal Consejo Superior de Investigaciónes Científicas
Contact: Centro de Investigaciónes Biológicas · Ramiro de Maeztu, 9. 28040 Madrid · Tel.: 91 837 31 12 E.mail: [email protected] · Website: http://www.cib.csic.es/es/Group.php?idGroup=7
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