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www.ciberehd.org

The results of this project will provide new knowledge about the possibility of non-

pharmacological treatment (weight loss) of portal hypertension in patients with
cirrhosis of the liver and excess weight/obesity.

A professional dietician had to be hired to perform follow-up once a week for the

first month and every two weeks after the second month.

BIOINFORMATICS PLATFORM

The primary objective of the Bioinformatics Platform is to provide support to re-
search staff in this area. In current research, where a flow of data resulting from

the massive data screening is obtained, this platform is a unit where any investiga-

tor that is a member of CIBERehd can have a rapid and customized solution.

The Platform works on developing and applying bioinformatics tools to analyze data
from high-throughput experiments (basically microarrays) to help develop medical

diagnostic kits.

Services offered by the platform:

• Development of new bioinformatics tools and applications

• File repository

• Project planning consulting and advisory services

CICBIOGUNE PLATFORM

The primary objective of this platform is to identify and validate genetic variants

(for example, polymorphisms of a single nucleotide or methylation differential)

involved in common complex human diseases. To that end, the complete genomes
of patients and the control used on all high-throughput genotyping and sequencing

techniques are studied.

Bioinformatics tools are also developed for data analysis. These tools supply a
biological result interpretation by means of examining the functionality of the iden-

tified genes, and by means of investigating their involvement in the etiology of

diseases and the possible mechanism of action.

Services offered by the Platform:

13
• 20
SSNP genotyping and cytogenetic analysis / CNV: T
OR
• Epigenetic analysis P
RE
• Whole genome expression L
A
• New generation sequencing
NU
N
A
D /
H
E
ER
IB
C

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