Page 34 - MemoriaDEM-Eng

HORIZONTAL PROGRAMMES AND PLATFORMS

• Universita Degli Studi Di Roma Tor Vergata, Department of Internal Medicine.
Rome, Italy.

• Ioannina University, Department of Endocrinology. Ioannina, Greece.

• Institute Of Biochemistry And Genetics, Ufa Scientific Center, Russian Academy of

Sciences. Bashkortostan, Russia.
• Institut Pasteur de Tunis, Research Unit on Genetic Orphan Diseases. Tunis, Tunisia.

• Univesity Of Alger 1, Laboratoire de Biochimie Génétique (LABIOGEN). Alger, Algeria.

• Institut Pasteur Du Maroc, Laboratoire de Génétique Moléculaire Humaine. Casa-

blanca, Morocco.

• University Hospital Of Tirana, Endocrinology Division. Tirana, Albania.
•
BC Platforms Ltd.
• PersonMed Ltd, Hungary.

• Istanbul University, Dept. Internal Midicine, Millet Caddesi. Istanbul, Turkey.

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The project began in fiscal year 2012 and continued in 2013. The total budget for the

4-year project is 371,644.00€ distributed as follows:

COST DISTRIBUTION

EU (75%)
CIBERDEM (25%)
PROJECT TOTAL

TOTAL CONTRIBUTION
278,733.00 €
92,911.00 €
371,644.00 €

CIBERDEM is involved in several work packages of the project and has various delive-
rables throughout its participation. CIBERDEM Biobank and several other Consortium

groups, such as the groups led by Dr. Luis Castaño and Dr. Ramon Gomis, will contribu-

te greatly to the project. In turn, the possible participation of other CIBERDEM groups
is currently under study.

In 2013, work continued to be done on WP1 “Anthropological studies and GWAS in

ethnic populations” and WP2 “Ancient DNA studies in Tarragona” of the project.

The work on WP1 consisted of selecting DNA samples from patients with metabolic
syndrome and the respective controls existing in CIBERDEM Biobank databases and

obtaining project approval from ethics committee. A total of 300 samples were obtai-

ned following strict selection criteria. These samples were analyzed through a genome-
wide association study (GWAS) together with another 1500 samples collected from all
à
over Europe and part of Africa by other MEDIGENE members.

CIBERDEM’s work on WP2 also continued in 2013 and consisted of determining the

genetics of ancient Roman populations in Tarragona and comparing it to modern po-
pulations of Catalonia and Italy as evidence of historical migrations and determining
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the prevalence of allelic variants. Various archaeological remains, primarily teeth, have 20
been identified in collaboration with the Institut Catal d’Arqueologia Clàssica (ICAC) T
R
of Tarragona, for obtaining ancient DNA samples. In 2013, CIBERDEM continued to PO
E
work on extracting DNA from samples of teeth for subsequent sample amplification L R
and analysis through NEXT-GEN genotyping in collaboration with the participants from A
NU
Universit Montpellier.
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