Page 63 - CIBERES-2015-eng

Most relevant scientific articles
Research Groups
torres a., siBiLa o., Ferrer M., PoLverino e., MenenDez r., Mensa J. et aL. Effect of corticosteroids on treatment failure among hospitalized patients with severe communi- ty-acquired pneumonia and high inflammatory response: A randomized clinical trial. JAMA - Journal of the Ameri- can Medical Association. 2015;313(7):677-686.
Prina e., ranzani o.t., torres a.. Community-acquired pneumonia. The Lancet. 2015;386(9998):1097-1108.
rinauDo M., Ferrer M., terraneo s., De rosa F., PeraL- ta r., FernánDez-Barat L. et aL. Impact of COPD in the outcome of ICU - Acquired pneumonia with and without previous intubation. Chest. 2015;147(6):1530-1538.
Highlights
It has been completed and published a clinical trial randomized double-blind administration of corti- costeroids in severe community-acquired pneumo- nia. The results demonstrate the beneficial effect of corticosteroids in reducing treatment failure. These results can be reviewed in more detail in the publica- tion : JAMA - Journal of the American Medical Asso- ciation. 2015;313(7):677-686.
We have been asked to write a review on the Com- munity acquired pneumonia in the Lancet Journal (The Lancet.2015;386(9998):1097-1108)
It has ended Gravity-VAP Trial study comparing the semi-recumbent position vs. lateral decubitus posi- tion rendelenburg for the prevention of pneumonia associated with artificial ventilation. It’s planned to publish the results for 2016.
Bassi g.L., Luque n., Marti J.D., xioL e.a., PasquaLe M.D., giunta v. et aL. Endotracheal tubes for critically ill patients: An in vivo analysis of associated tracheal inju- ry , mucociliary clearance, and sealing effi cacy. Chest. 2015;147(5):1327-1335.
CiLLoniz C., aLBert r.K., LiaPiKou a., gaBarrus a., ran- geL e., BeLLo s. et aL. The effect of macrolide resistance on the presentation and outcome of patients hospital- ized for streptococcus pneumoniae pneumonia. Amer- ican Journal of Respiratory and Critical Care Medicine. 2015;191(11):1265-1272.
We have developed an animal model of streptococ- cus pneumoniae in mechanically ventilated pigs for more than 72 hours. Specifically it was used serotype 19A. These results were presented as an Abstract at the last Congress of the European Respiratory Soci- ety and in the SEPAR.
Many contracts have been signed with the following industries for studies in Animal Model: Mediimmune, Cardeas, Arsanis and Theravance.
They were presented 3 doctoral thesis of group members or researcher sassociated with it in the 2015.
The IP of the group is co-leader of the European Pro- ject WP4A COMBACTE MAGNET.
Institution: Hospital Clínic de Barcelona · Contact: Villarroel, 170. 08036 Barcelona
Tel.: 93 227 55 49 · E.mail: [email protected] · Website: http://www.idibapsrespiratoryresearch.org
CIBERES I Annual report 2015 I 63