Page 11 - CIBEREHD-2015-eng

Significant activities
Projects
The projects active in 2015 were as follows:
NATIONAL PROJECTS
Financing agency: Instituto de Salud Carlos III
• Financing agency: Instituto de Salud Carlos III
• Characterisation of microRNAs in pancreatic cancer: from new biomarkers to therapeutic tar- gets.
• Clinical effectiveness and safety in the intrale- sional administration of tolerogenic dendritic cells in patients with refractory Crohn’s disease.
• Virological and immunological factors connect- ed with antiviral treatment and the recurrence of hepatitis C after a liver transplant.
• Implementation of a tool based on ultra-sequenc- ing to determine sub-genotypes of the hepatitis C virus: optimisation of the treatment.
• Implication of the extra-cell matrix in the appear- ance of progressive complications in Crohn’s dis- ease and in the development of new therapeutic proposals.
• Understanding obesity (OB), metabolic syndrome (METS), type 2 diabetes (T2DM) and fatty liver disease (FL): a multidisciplinary approach.
• Impact in treatment of new antivirals on the nat- ural history of cirrhosis through the hepatitis C virus. Identification of factors predicting no re- sponse. Part A: Impact of treatment with new direct-acting antivirals on the natural history of chronic advanced hepatopathy (cirrhosis) and pathogenic mechanisms.
• Impact in treatment of new antivirals on the nat- ural history of cirrhosis through the hepatitis C virus. Identification of factors predicting no re- sponse. Separation B optimisation of direct an- tiviral treatment of chronic Hepatitis C in clinical practice and identification of the factors associat- ed with the lack of response.
• Rio Hortega Contract.
Financing agency: Ministry of the Economy and Competitiveness:
• Development of a Kit for early diagnosis of colorectal cancer – Detection in plasma (miR- NAs).
Other financing agencies:
• Fundació la Marató de TV3: “Anàlisi per biología de sistemes de la tolerància immunitària en trasplantament d’òrgans.”
• Proyecto AECC.
We should stress the participation of the CIBERE- HD in two of the interdisciplinary CIBER excellence projects financed by the AES. The project led by Dr José María Mato (CIBEREHD) will attempt to iden- tify biomarkers for the early diagnosis of the met- abolic syndrome (MS) and to find new therapeutic approaches. The CIBEREHD also takes part in an- other of the projects led by CIBERDEM which inves- tigates inflammation in diverse diseases to obtain therapies.
Technology transfer
One of the CIBER’s main aims is the transfer of re- search results to clinical practice, and one of the best tools existing for this purpose is technology transfer. The Unit managing this at the CIBER sets out to act as a bridge between our researchers and other agents in the Science and Technology System (companies, business associations, other research organisations, etc.) to make cooperation with these bodies more effective. This means that research re- sults will be efficiently developed and can succeed in being applied. Work is done in several lines to this end:
• Training in innovation management and contin- uous contact with our researchers to monitor their results.
In this respect, last year the first general event of the CIBER in training on technology transfer and innovation was held, on 26th February 2015, where national experts took part sharing their knowledge in matters such as industrial proper- ty, business creation or open access publication, etc.
Organization
CIBEREHD I Annual report 2015 I 11