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Lines of Research.
• To continue the study of the follow-up and predictive variables in first psychotic episodes .
The results of the FPE study on first psychotic episodes have begun to be published in 2014 . Work has been continued on the second project on FPEs, both of which are coordinated by Dr . M . Bernardo . The first results of the European project EU-GEI, coordinated in Spain by Dr . C . Arango, have also been published .
• To study the possible neurobiological (genetic, immunological and neuroimaging) markers of different symptomatological phenotypes of schizophrenia .
The main results of the GWAS study, which replicate the findings of broad genome studies in a sample of over 3000 patients diagnosed with schizophrenia, have been published in 2014 .
• Study the predictive response variables (neuroimaging, neuroimmunology, neurophysiology) in relation to different pharmacological treatments .
Various basic CIBERSAM groups have published and proposed new antipsychotic response prediction models . There have also been important contributions concerning the role of immunological response as a prognosis variable in these patients .
• To conduct research on the efficacy and effectiveness of psychotherapeutic treatments in combination with standard pharmacological treatments in schizophrenia .
Several European projects have been initiated which include the participation of CIBERSAM groups (Dr . Arango, Dr . Crespo-Facorro, Dr . Bernardo) . The main objectives of these projects, among others, are optimisation of pharmacological and psychosocial treatment .
• To study the repercussions of schizophrenia on the state of health, psychosocial adjustment, quality of life, the individual’s levels of disability and on patient service use patterns and the effect on comorbidity .
The research meeting on Psychosis, including the participation of family members of these patients, was held again . Various multicentre projects concerning the importance of physical health in schizophrenic patients, with a particular emphasis on metabolic disorder, were started up .
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