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PROGRAMME 2
Mechanisms involved in the development of diabetes and its vascular complications. Associated co-morbidities. Strategies for prevention and treatment.
Objectives:
• Identification of neurodegenerative mechanisms which promote the development of diabetic retinopathy: the role of insulin signaling and apoptosis .
• Glycogen-induced dysfunctions in the pancreas and retina and the involvement thereof in the etiopathogenesis of diabetes mellitus .
• Mechanisms of endothelial dysfunction in diabetes: the role of amylin and circulating endothelial cells .
• The influence of insulin resistance and the compensatory response of the endocrine pancreas on endothelial/vascular damage .
Coordinator: Dr. Manuel Benito Associated groups: 9
Lead researcher
Institution
Region
Benito de las Heras, Manuel Román
Universidad Complutense de Madrid
Madrid
Blanco Vaca, Francisco
Instituto de Investigación del Hospital de la Santa Cruz y San Pablo
Cataluña
Gomis de Bárbara, Ramón
Instituto de Investigaciones Biomédicas August Pi i Sunyer
Cataluña
Guinovart Cirera, Joan Josep
Fundació Privada Institut de Recerca Biomèdica (IRB)
Cataluña
Martinez Valverde, Ángela María
Consejo Superior de Investigaciones Científicas
Madrid
Masana Marin, Luis
Fund . Institut d’Investigació Sanitaria Pere Virgili
Cataluña
Simo Canonge, Rafael
Fund . Instituto de Investigación Vall D’hebron
Cataluña
Vendrell Ortega, Joan J .
Fund . Institut d’Investigació Sanitaria Pere Virgili
Cataluña
Egido De los Ríos, Jesús
Instituto de Investigación Sanitario Fundación Jiménez Díaz
Madrid
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