Page 21 - MemoriaDEM-Eng

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Programme 2

Á

óí
Mechanisms involved in the development of diabetes and its

vascular complications. Associated co-morbidities. Strategies
for prevention and treatment.
áí
ááú
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Coordinator: Dr. Manuel Benito

Associated groups: 10

• Identification of neurodegenerative mechanisms which promote the develop-
Objectives
ment of diabetic retinopathy: the role of insulin signaling and apoptosis.
é
• Glycogen-induced dysfunctions in the pancreas and retina and the involve-

ment thereof in the etiopathogenesis of diabetes mellitus.
ó

• Mechanisms of endothelial dysfunction in diabetes: the role of amylin and cir- í
culating endothelial cells.

•
The influence of insulin resistance and the compensatory response of the en-
docrine pancreas on endothelial/vascular damage.

óó

PI Name
Consortium Institution
AUTO.
óóCOMM.
ó
Benito de las Heras, Universidad Complutense de Madrid
Madrid
Manuel Romn
é
Blanco Vaca, Francisco
Instituto de Investigacin del Hospital de la Madrid
Santa Cruz y San Pablo

Gomis de Brbara, Instituto de Investigaciones Biomdicas August
Ramn
Pi i Sunyer
Catalonia
èó
Guinovart Cirera, Joan Fundaci Privada Institut de Recerca Biomdica 13
Josep
(IRB)
óCatalonia
20
T
De Pablo Dvila, Flora
Consejo Superior de Investigaciones Cientificas
Madrid
OR
P
Martnez Valverde, RE
ngela Mara
Consejo Superior de Investigaciones Cientificas
Madrid
L
A
Masana Marin, Luis
Fund. Institut d’Investigaci Sanitaria Pere Virgili
Catalonia
NU
N
Simo Canonge, Rafael
Fund. Instituto de Investigacin Valle de Hebrn
Catalonia
A
M /
Vendrell Ortega, Joan J.
Fund. Institut d’Investigaci Sanitaria Pere Virgili
Catalonia
E
D
Villanueva-Peacarrillo, Instituto de Investigacin Sanitario Fundacin ER
Ma Luisa/Jess Egido
Jimnez Daz
Madrid
B
CI

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